There are no fixes for that Runtime Error in the stickies. I should probably dig around the old threads and correct this.

For now though, Verify the Integrity of the Game Cache, and if that doesn't fix it re-install DirectX.

How can I verify the Integrity of the Game's Cache when I didn't download it off Steam?

I bought the Humble Bundle V, and I didn't download this off Steam. The game keeps giving me a Microsoft Runtime C++ Library error. Is there any way I can get it to work?