Hey guys, Not sure if i should reply here, but feel free to move to the appropriate forum.

 I just created an account because i found somewhat of a solution for those having problems with crossfire setups. I have 2x6850HD and i was having some glitch where the landing animation was playing while the character was idle; Also the game was kinda running like 2 times faster or something like that.

Disabling Crossfire fixes it, but if you don't want to go and disable it every single time you want to play the game, just create a crossfire profile for the game disabling and disable the crossfire on it.

After that every time you run the game the crossfire will be disable allowing you to play normally. This worked for me perfectly nice, but there's not much info about it out there, so i just wanted to share that little piece of knowledge.

Hope this fixes your issues!
EDIT: After a little more digging, this is the issue i was running into with crossfire but it didn't end at anytime; only when crossfire was disabled.
http://smb.thecybershadow.net/Main_Page#Meat_Boy_.22spazzes.22_out

PS. Attached a screenshot of my settigs...